Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2548)
Related Products (2548)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Benzimidazole (Standard)
0 ImagesBenzimidazole (Standard) is the analytical standard of Benzimidazole. This product is intended for research and analytical applications. Benzimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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(+)-Neomenthol
0 ImagesCat. No.: HY-135286ACAS No.: 2216-52-6(+)-Neomenthol is a potent miticide. (+)-Neomenthol shows acaricidal activitie with LD50 values of 0.32, 0.256 µg/mL for Dermatophagoides farinae and Dermatophagoides pteronyssinus, respectively.
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S-Methyl thioacetate
0 ImagesCat. No.: HY-W102349CAS No.: 1534-08-3S-Methyl thioacetate is a toxicant with fumigant activity, can be found in emissions from Bacillus oshimensis, Burkholderia gladioli, Burkholderia cepacia, and Pseudomonas oryzihabitans. S-Methyl thioacetate exerts fumigant toxicity against Caenorhabditis elegans and root-knot nematode Meloidogyne incognita. S-Methyl thioacetate functions as a bacterial volatile organic compound. S-Methyl thioacetate can be used for the research of plant-parasitic nematode infection.
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Fluacrypyrim
0 ImagesCat. No.: HY-W414644CAS No.: 229977-93-9Fluacrypyrim, a Miticide, is a STAT3 inhibitor. Fluacrypyrim significantly increases the protein tyrosine phosphatases(PTPs) activity. Fluacrypyrim inhibits the growth of leukemia cells by a predominant G1 arrest with significant decrease of the protein and mRNA levels of cyclin D1. Fluacrypyrim selectively inhibits STAT3 signaling, inducing growth arrest and apoptosis in STAT3-dependent cancer cells. Fluacrypyrim mitigates IR-induced hematopoietic system injury mainly by preventing apoptosis in the HSCs. Fluacrypyrim demonstrates significant analgesic and anti-inflammatory effects by inhibiting uterine smooth muscle contraction and inflammatory responses.
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PfDHODH-IN-2
0 ImagesPfDHODH-IN-2, a dihydrothiophenone derivative (Compound 11), is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor with an IC50 of 1.11 µM. PfDHODH-IN-2 acts as an antimalarial agent and can be used for the research of malaria.
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Aluminum phthalocyanine chloride
0 ImagesCat. No.: HY-129959CAS No.: 14154-42-8Synonyms: AlClPcAluminum phthalocyanine chloride is a photosensitizer that effectively inhibits the parasite Leishmania amazonensis (the causative agent of cutaneous leishmaniasis) by light-mediated cytolysis. Aluminum phthalocyanine chloride causes parasite morphology and cytolysis of isolated amasilians, while higher photosensitizer concentrations and light intensities are required to induce lysis of mammalian cells. Aluminum phthalocyanine chloride lyses parasites within infected J774 macrophages and can be used to further investigate the study of leishmaniasis.
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Digitolutein
0 ImagesDigitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of Plasmodium falciparum with an IC50 value of 12.92 μg/mL. Digitolutein can be used for the research of infection.
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Tongkat Ali Extract
0 ImagesCat. No.: HY-N13215Tongkat Ali Extract is the extract of Tongkat Ali, a testosterone modulator. Tongkat Ali Extract activates CYP17 enzyme to enhance conversion of pregnenolone and progesterone to dehydroepiandrosterone, androstenedione, and testosterone. Tongkat Ali Extract demonstrates antimalarial, antimicrobial, anticancer, and antidiabetic activity. Tongkat Ali Extract can be used for the research of diabetic and male infertility.
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SR9186
0 ImagesSynonyms: ML368SR9186 (ML368) is a selective CYP3A4 inhibitor with IC50 values of 9, 4, and 38 nM for Midazolam → 1'-hydroxymidazolam, Testosterone → 6β-hydroxytestosterone, and Vincristine → Vincristine M1, respectively. SR-9186 inhibits the development of hepatic-stage P. falciparum and blocks ivermectin metabolism. SR-9186 can be used in breast cancer research.
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Proguanil-d6
0 ImagesCat. No.: HY-B0806SCAS No.: 2070014-86-5Proguanil-d6 is the deuterium labeled Proguanil, which is a prophylactic antimalarial agent.
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(+)-Isopulegol
0 Images(+)-Isopulegol is a terpenoid found in Mentha canadensis L. (+)-Isopulegol shows phagostimulatory activity towards adults of S. granarius and T. confusum. (+)-Isopulegol is a feeding attractant for adults of T. confusum and T. granarium larvae.
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8a-OH-Avermectin B1a
0 Images8a-OH-Avermectin B1a is a key primary monooxygenated degradate generated during the photodegradation of Avermectin B1a (HY-15308). 8a-OH-Avermectin B1a can be used for the study of antiparasitic infection.
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Afoxolaner (Standard)
0 ImagesAfoxolaner (Standard) is the analytical standard of Afoxolaner. This product is intended for research and analytical applications. Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.
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Dill apiole
0 ImagesDill apiole is an aromatic ether, which is an important aroma component in herbs and spices such as dill (Anethum graveolens), parsley (Petroselinum crispum) and basil (Perilla frutescens). Dill apiole exhibits antimicrobial activity against Aspergillus parasiticus and Aedes aegypti.
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Nitromide
0 ImagesNitromide is an anti-parasitic agent.
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Anisofolin A
0 ImagesAnisofolin A is a flavonoid that can be isolated from Anisomeles indica. Anisofolin A has antimalarial activity (IC50: 4.39 μM), and antimycobacterium activity (IC50: 4.50 μM) against M. tuberculosis H37Ra.
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2-Benzoxazolinone (Standard)
0 ImagesSynonyms: 2-Benzoxazolone (Standard); 1,3-Benzoxazol-2(3H)-one (Standard); 2-Hydroxybenzoxazole (Standard)2-Benzoxazolinone (Standard) is the analytical standard of 2-Benzoxazolinone. This product is intended for research and analytical applications. 2-Benzoxazolinone is an anti-leishmanial agent with an LC50 of 40 μg/mL against L. donovani. A building block in chemical synthesis. 1,3-Benzoxazol-2(3H)-one derivatives have antimicrobial activity against a selection of Gram-positive, Gram-negative bacteria and yeasts. Derivatives as anti-quorum sensing agent[4].
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Halofuginone hydrobromide (Standard)
0 ImagesSynonyms: RU-19110 hydrobromide (Standard)Halofuginone hydrobromide (Standard) (RU-19110 hydrobromide (Standard)) is the analytical standard of Halofuginone hydrobromide (HY-N1584A). This product is intended for research and analytical applications. Halofuginone hydrobromide (RU-19110 hydrobromide), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromide is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromide is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrobromide has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.
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Antileishmanial agent-32
0 ImagesCat. No.: HY-W097659CAS No.: 16929-60-5Antileishmanial agent-32 (Compound 12) exhibits a weak antileishmanial activity that inhibits stationary promastigote forms of L. amazonensis with an IC50 >15 μM. Antileishmanial agent-32 exhibits cytotoxicity towards murine macrophages.
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Milbemycin oxime (Standard)
0 ImagesMilbemycin oxime (Standard) is the analytical standard of Milbemycin oxime. This product is intended for research and analytical applications. Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms.
